[HTML][HTML] Molecular assessment of microcirculation injury in formalin-fixed human cardiac allograft biopsies with antibody-mediated rejection
Precise diagnosis of antibody-mediated rejection (AMR) in cardiac allograft endomyocardial
biopsies (EMBs) remains challenging. This study assessed molecular diagnostics in human
EMBs with AMR. A set of 34 endothelial, natural killer cell and inflammatory genes was
quantified in 106 formalin-fixed, paraffin-embedded EMBs classified according to 2013
International Society for Heart and Lung Transplantation (ISHLT) criteria. The gene set
expression was compared between ISHLT diagnoses and correlated with donor-specific …
biopsies (EMBs) remains challenging. This study assessed molecular diagnostics in human
EMBs with AMR. A set of 34 endothelial, natural killer cell and inflammatory genes was
quantified in 106 formalin-fixed, paraffin-embedded EMBs classified according to 2013
International Society for Heart and Lung Transplantation (ISHLT) criteria. The gene set
expression was compared between ISHLT diagnoses and correlated with donor-specific …