Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study

C Meier, TV Nguyen, DJ Handelsman… - Archives of internal …, 2008 - jamanetwork.com
Background Data on the influence of gonadal hormones on incident fracture risk in elderly
men are limited. We prospectively examined the relationship between serum levels of
testosterone and estradiol and future fracture risk in community-dwelling men. Methods A
total of 609 men older than 60 years had been observed between January 1989 and
December 2005, with the median duration being 5.8 years (up to 13 years). Clinical risk
factors, including bone mineral density and lifestyle factors, were assessed at baseline …