[HTML][HTML] CXCR4 expression correlates with the degree of tumor infiltration and BRAF status in papillary thyroid carcinomas
L Torregrossa, R Giannini, N Borrelli, E Sensi… - Modern Pathology, 2012 - Elsevier
Emerging evidence indicates that interactions between chemokine receptors and their
ligands may have a critical role in several steps of tumor development, including tumor
growth, progression, and metastasis. In this report, we retrospectively evaluated CXCR4
expression in a consecutive series of 200 papillary thyroid carcinomas. We investigated the
relationship between the clinicopathological features of the tumors and mutations in the
BRAF gene to verify whether overexpression of CXCR4 is linked to more aggressive …
ligands may have a critical role in several steps of tumor development, including tumor
growth, progression, and metastasis. In this report, we retrospectively evaluated CXCR4
expression in a consecutive series of 200 papillary thyroid carcinomas. We investigated the
relationship between the clinicopathological features of the tumors and mutations in the
BRAF gene to verify whether overexpression of CXCR4 is linked to more aggressive …
