The relationship between hemoglobin A1c values and healing time for lower extremity ulcers in individuals with diabetes

M Markuson, D Hanson, J Anderson… - Advances in skin & …, 2009 - journals.lww.com
M Markuson, D Hanson, J Anderson, D Langemo, S Hunter, P Thompson, R Paulson…
Advances in skin & wound care, 2009journals.lww.com
RESULTS: Of the 63 ulcers, 36 healed, 26 did not heal, and it was not possible to determine
if healing occurred for 1 ulcer. Admission HgbA 1c values ranged from 4.5 to 15.4 (mean,
8.05 [SD, 2.29]). HgbA 1c values closest to ulcer closure ranged from 5.3 to 12.3 (mean, 7.68
[SD, 1.81]). It was found that patients with higher HgbA 1c levels did experience wound
healing, but in a significantly longer period than those with lower HgbA 1c. Individuals with
type 1 diabetes had a higher healing rate (77.8%) than individuals with type 2 diabetes …
RESULTS:
Of the 63 ulcers, 36 healed, 26 did not heal, and it was not possible to determine if healing occurred for 1 ulcer. Admission HgbA 1c values ranged from 4.5 to 15.4 (mean, 8.05 [SD, 2.29]). HgbA 1c values closest to ulcer closure ranged from 5.3 to 12.3 (mean, 7.68 [SD, 1.81]). It was found that patients with higher HgbA 1c levels did experience wound healing, but in a significantly longer period than those with lower HgbA 1c. Individuals with type 1 diabetes had a higher healing rate (77.8%) than individuals with type 2 diabetes (53.7%), whereas 40% of all closed ulcers reopened. A significant correlation was also noted between a history of smoking and increased HgbA 1c levels.
IMPLICATIONS:
Healing times were decreased in those individuals who had lower HgbA 1c values. Decreased healing times result in lower cost for the patient, decreased chance of infection due to lack of portal of entry, and increased quality of life. Patient education may increase self-care practices in the diabetic population regarding better glucose control.
Lippincott Williams & Wilkins